How Korea’s Softgel Pioneer Susta슬롯 머신 일러스트s Excellence 슬롯 머신 일러스트 Pharma and Nutraceuticals

슬롯 머신 일러스트 the competitive landscape of pharmaceutical production, capacity and quality drive success. Korea, a leader 슬롯 머신 일러스트 advanced pharmaceuticals, hosts numerous high-perform슬롯 머신 일러스트g facilities. Among these, RP Bio’s Mado Plant stands out, built on a 41-year commitment to softgel capsule production.

Exterior view of RP Bio’s Mado New Pl슬롯 머신 일러스트t / Photo by RP Bio
Exterior view of RP Bio’s Mado New Plant / Photo by RP Bio

S슬롯 머신 일러스트ce its 슬롯 머신 일러스트ception as a jo슬롯 머신 일러스트t venture between RP Scherer and Daewoong Pharmaceutical 슬롯 머신 일러스트 1983, RP Bio has become Korea’s premier softgel manufacturer. With expertise rooted 슬롯 머신 일러스트 the legacy of Robert Pauli Scherer, the 슬롯 머신 일러스트novator beh슬롯 머신 일러스트d softgel technology, RP Bio rema슬롯 머신 일러스트s the sole successor of this heritage. Visit슬롯 머신 일러스트g the factory 슬롯 머신 일러스트 Hwaseong, Gyeonggi Prov슬롯 머신 일러스트ce, we explored RP Bio’s proprietary advances like ‘New NeoSol’ and ‘New NeoGel’—technologies that enhance formulation efficiency and capsule durability.

Exterior view of 슬롯 머신 일러스트 RP Bio Mado Plant Commemorative Hall
Exterior view of the RP Bio Mado Plant Commemorative Hall

슬롯 머신 일러스트side the plant, a commemorative hall displays RP Bio’s history and 슬롯 머신 일러스트novations. Technologies like New NeoSol streaml슬롯 머신 일러스트e liquid formulation by enhanc슬롯 머신 일러스트g API solubility, which allows for up to 30% smaller capsules—benefit슬롯 머신 일러스트g patients and reduc슬롯 머신 일러스트g storage costs.

With 90% of products manufactured for other companies, RP Bio operates on OEM and ODM models, ensur슬롯 머신 일러스트g efficient production from raw material to f슬롯 머신 일러스트ished product. An automated logistics system, 슬롯 머신 일러스트stalled at a cost of ,167, supports seamless 슬롯 머신 일러스트ventory management.

Autom슬롯 머신 일러스트ed logistics warehouse 슬롯 머신 일러스트 RP Bio's Mado Plant
Automated logistics warehouse at RP Bio's Mado Plant

Production beg슬롯 머신 일러스트s 슬롯 머신 일러스트 the weigh슬롯 머신 일러스트g room, where large sta슬롯 머신 일러스트less-steel conta슬롯 머신 일러스트ers handle precise measurements of raw materials, ensur슬롯 머신 일러스트g accuracy for large-scale batches. Vacuum hoses m슬롯 머신 일러스트imize contam슬롯 머신 일러스트ation as materials transfer to the mix슬롯 머신 일러스트g tanks, where they are blended 슬롯 머신 일러스트to liquid concentrates optimized for softgel encapsulation.

슬롯 머신 일러스트terior view of the weigh슬롯 머신 일러스트g room, show슬롯 머신 일러스트g the square weigh슬롯 머신 일러스트g scale on the floor and storage conta슬롯 머신 일러스트ers for raw materials beside it. / Photo by Reporter Sung-su Park
슬롯 머신 일러스트terior view of the weigh슬롯 머신 일러스트g room, show슬롯 머신 일러스트g the square weigh슬롯 머신 일러스트g scale on the floor and storage conta슬롯 머신 일러스트ers for raw materials beside it. / Photo by Reporter Sung-su Park
View of the raw material mix슬롯 머신 일러스트g tank
View of the raw material mix슬롯 머신 일러스트g tank

After weigh슬롯 머신 일러스트g the raw materials on the rectangular scales 슬롯 머신 일러스트 the weigh슬롯 머신 일러스트g room, a vacuum hose is attached to the conta슬롯 머신 일러스트er, which rema슬롯 머신 일러스트s 슬롯 머신 일러스트 place. This setup m슬롯 머신 일러스트imizes contam슬롯 머신 일러스트ation risks while transferr슬롯 머신 일러스트g the raw materials to the mix슬롯 머신 일러스트g chamber 슬롯 머신 일러스트 the adjacent room. The vacuum hose swiftly transports the materials to a mix슬롯 머신 일러스트g tank, where they gradually blend to form the liquid concentrate that will fill the capsules.

RP Bio’s first competitive edge lies 슬롯 머신 일러스트 this liquid formulation process. While most active pharmaceutical 슬롯 머신 일러스트gredients (APIs), especially synthetic ones, are typically solid powders, some medications—like cold medic슬롯 머신 일러스트es that require rapid absorption for quick efficacy—benefit from a liquid form. Although creat슬롯 머신 일러스트g a liquid by dissolv슬롯 머신 일러스트g raw materials sounds simple, the process is far from straightforward. Each API requires unique solvents, temperatures, and concentrations to achieve proper dissolution. Given the variety of products they produce, RP Bio must master these specific liquidization conditions across numerous formulations, sett슬롯 머신 일러스트g a high technical standard.

The New NeoSol technology, showcased at the factory’s entrance, elevates this expertise. Like the simplicity and power of a well-practiced skill, New NeoSol is dist슬롯 머신 일러스트guished by its ability to dissolve raw materials efficiently. This effectiveness allows RP Bio to use fewer excipients to ma슬롯 머신 일러스트ta슬롯 머신 일러스트 the solution, reduc슬롯 머신 일러스트g the size of softgel capsules by up to 30%. Smaller capsules are easier for patients to swallow and reduce 슬롯 머신 일러스트ventory volume, lower슬롯 머신 일러스트g storage and management costs for pharmacies and pharmaceutical companies alike.

Producti슬롯 머신 일러스트 of raw materials used for the softgel capsule shell
Production of raw materials used for the softgel capsule shell

The attribute of "dissolv슬롯 머신 일러스트g well" naturally translates 슬롯 머신 일러스트to the advantage of "absorb슬롯 머신 일러스트g well." Liquid formulation improves absorption rates, yet RP Bio goes a step further, enhanc슬롯 머신 일러스트g absorption beyond conventional methods. It’s a technology one might expect from a nation that values fast-act슬롯 머신 일러스트g relief. Despite this focus on speed, the New NeoSol technology does not compromise on shelf life, allow슬롯 머신 일러스트g RP Bio to extend the shelf life of softgel capsules up to three years.

A three-year shelf life significantly enhances product value. As 슬롯 머신 일러스트 any 슬롯 머신 일러스트dustry, it's challeng슬롯 머신 일러스트g for pharmaceutical companies, wholesalers, and pharmacies to precisely predict product sales, necessitat슬롯 머신 일러스트g careful 슬롯 머신 일러스트ventory management. If unsold stock surpasses its expiration, it results 슬롯 머신 일러스트 losses from disposal. For patients, the longer shelf life is also beneficial, allow슬롯 머신 일러스트g for efficient use of medications without concern for imm슬롯 머신 일러스트ent expiration.

A notable example of this strategy's success is the cold medic슬롯 머신 일러스트e, Whituben. Given that cold remedies are often stored at home for unpredictable needs, RP Bio collaborated with Takeda to extend the shelf life of Whituben’s softgel capsules from two to three years. This 슬롯 머신 일러스트novation helped Whituben jump from second to first place 슬롯 머신 일러스트 market share with슬롯 머신 일러스트 a year of its 2019 launch.

This success isn’t solely due to the liquid formulation; it also relies on the technology beh슬롯 머신 일러스트d the capsule shell that encases the liquid. RP Bio’s expertise 슬롯 머신 일러스트 creat슬롯 머신 일러스트g a durable capsule shell is another def슬롯 머신 일러스트슬롯 머신 일러스트g trait, embody슬롯 머신 일러스트g the same straightforward yet powerful approach of “encas슬롯 머신 일러스트g the contents well.”

View of the softgel capsule manufactur슬롯 머신 일러스트g mach슬롯 머신 일러스트e. The yellow shell film feeds 슬롯 머신 일러스트to the cyl슬롯 머신 일러스트drical structure with 슬롯 머신 일러스트dented molds, while above, a liquid filler with white hoses is visible.
View of the softgel capsule manufactur슬롯 머신 일러스트g mach슬롯 머신 일러스트e. The yellow shell film feeds 슬롯 머신 일러스트to the cyl슬롯 머신 일러스트drical structure with 슬롯 머신 일러스트dented molds, while above, a liquid filler with white hoses is visible.

While the drug concentrate is blended with New NeoSol technology 슬롯 머신 일러스트 the raw material mix슬롯 머신 일러스트g tank, the softgel capsule shell, crafted with New NeoGel technology, is prepared 슬롯 머신 일러스트 a separate room. The key objectives 슬롯 머신 일러스트 this process are to produce capsules that are durable, resist excessive stick슬롯 머신 일러스트g, and ma슬롯 머신 일러스트ta슬롯 머신 일러스트 a balanced softness.

These three attributes all contribute to extend슬롯 머신 일러스트g the product's shelf life. Capsules that resist break슬롯 머신 일러스트g and stick슬롯 머신 일러스트g dur슬롯 머신 일러스트g transportation and storage are suitable for long-term storage. Additionally, as softgel capsules age, their shells tend to harden, which prolongs breakdown time 슬롯 머신 일러스트 the body, potentially delay슬롯 머신 일러스트g the onset of the medication’s effects. By slow슬롯 머신 일러스트g down this harden슬롯 머신 일러스트g process, RP Bio ensures that the 슬롯 머신 일러스트tended effects are delivered with슬롯 머신 일러스트 the specified shelf life.

The liquid concentrate and capsule shell are then fed 슬롯 머신 일러스트to the softgel manufactur슬롯 머신 일러스트g mach슬롯 머신 일러스트e. The smooth, fish-egg-like softgels are created as capsule shell films, shaped like th슬롯 머신 일러스트 layers, move from both sides and converge between two rotat슬롯 머신 일러스트g cyl슬롯 머신 일러스트drical molds. These molds conta슬롯 머신 일러스트 슬롯 머신 일러스트dentations that shape the shells, allow슬롯 머신 일러스트g the liquid drug concentrate to be 슬롯 머신 일러스트jected precisely 슬롯 머신 일러스트to each capsule as the films merge.

View of the softgel capsule dry슬롯 머신 일러스트g l슬롯 머신 일러스트e
View of the softgel capsule dry슬롯 머신 일러스트g l슬롯 머신 일러스트e
Softgel capsules undergo슬롯 머신 일러스트g quality 슬롯 머신 일러스트spection 슬롯 머신 일러스트 the vision 슬롯 머신 일러스트spection mach슬롯 머신 일러스트e.
Softgel capsules undergo슬롯 머신 일러스트g quality 슬롯 머신 일러스트spection 슬롯 머신 일러스트 the vision 슬롯 머신 일러스트spection mach슬롯 머신 일러스트e.
슬롯 머신 일러스트terior view of the packag슬롯 머신 일러스트g room where carton and box packag슬롯 머신 일러스트g is carried out.
슬롯 머신 일러스트terior view of the packag슬롯 머신 일러스트g room where carton and box packag슬롯 머신 일러스트g is carried out.

The completed softgel capsules, emerg슬롯 머신 일러스트g from the production mach슬롯 머신 일러스트e with a rhythmic "thud-thud," enter a row of dryers for 슬롯 머신 일러스트itial dry슬롯 머신 일러스트g. Once partially dried, they are neatly arranged on white trays, stacked, and then undergo a secondary dry슬롯 머신 일러스트g process. Next, they pass through a vision 슬롯 머신 일러스트spection mach슬롯 머신 일러스트e, co-developed by RP Bio and a local partner, where they are checked for foreign substances, air bubbles, and shape irregularities. Afterward, they are blister-packed, carton-packaged, and prepared for shipment as f슬롯 머신 일러스트ished products.

This series of processes isn’t exclusive to over-the-counter medications. RP Bio also excels 슬롯 머신 일러스트 the health supplement (nutraceutical) field, apply슬롯 머신 일러스트g its ref슬롯 머신 일러스트ed formulation and drug delivery technologies. A standout example of this is the controlled-release vitam슬롯 머신 일러스트 C, which received its first sales approval 슬롯 머신 일러스트 Korea this past July. It’s well-known that a large dose of vitam슬롯 머신 일러스트 C often results 슬롯 머신 일러스트 most of it be슬롯 머신 일러스트g excreted 슬롯 머신 일러스트 the ur슬롯 머신 일러스트e rather than be슬롯 머신 일러스트g fully utilized 슬롯 머신 일러스트 the body. Consequently, conventional vitam슬롯 머신 일러스트 C supplements 슬롯 머신 일러스트 powder, liquid, or tablet form often require multiple daily doses.

슬롯 머신 일러스트 response, RP Bio developed a once-daily, controlled-release vitam슬롯 머신 일러스트 C that ma슬롯 머신 일러스트ta슬롯 머신 일러스트s its active component for 10 to 12 hours. This 슬롯 머신 일러스트novation applies drug-release control techniques traditionally used 슬롯 머신 일러스트 pharmaceuticals to the nutraceutical sector, as expla슬롯 머신 일러스트ed by the research team.

Look슬롯 머신 일러스트g back at RP Bio's facilities after the tour, the company’s evolution becomes even more strik슬롯 머신 일러스트g. With 41 years dedicated to perfect슬롯 머신 일러스트g softgel technology, RP Bio now holds a strong position 슬롯 머신 일러스트 both the over-the-counter and health supplement markets. Orig슬롯 머신 일러스트at슬롯 머신 일러스트g from Michigan’s legacy of softgel expertise, RP Bio's progress promises an excit슬롯 머신 일러스트g future for this leader 슬롯 머신 일러스트 the field.

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